Endocrine Abstracts

Patients with congenital adrenal hyperplasia (CAH) require life-long, daily glucocorticoid hormone replacement therapy. Currently, there is no licensed treatment for young patients and existing treatment requires adapting adult doses by crushing tablets. As primary caregivers, parents of young children with CAH often take on the responsibility for routine medication and adapting doses in times of stress or illness. There has been little research to date exploring parents’...

Congenital adrenal hyperplasia (CAH) is a genetic condition associated with a deficiency in cortisol and an overproduction of androgens, requiring life-long, daily medication. Little is known about the psychosocial impact of living with and treating CAH, particularly for the parents of young patients. The study was conducted by Genetic Alliance UK as part of the European Commission funded Treatment of Adrenal Insufficiency in Neonates (TAIN) Project, which aims to develop a ne...

Pneumocystis jirovecii pneumonia (PJP) is well recognised in HIV infected and transplant recipient populations and prophylaxis is standard practice. PJP may also occur in rarer cases of immunodeficiency. We report 2 cases of Cushing’s syndrome complicated by PJP. Patient 1 was a 30 year old Indian male who presented with 2 weeks of bloody diarrhoea, abdominal pain and lethargy. He was cushingoid and investigations showed severe hypercortisolism (urinary cortisol >266,...